EU leaders have officially launched the competition between member states to decide which will host two London-based EU agencies, responsible for medicines and banking.
The relocation must take place by the Brexit deadline – 30 March 2019.
Some countries are bidding to host both the European Medicines Agency (EMA) and European Banking Authority (EBA).
It means hundreds of jobs moving from London, along with significant revenue from hotel stays and conferences.
The deciding vote will take place in November.
The EU 27 agreed on the selection process on Thursday night, after UK Prime Minister Theresa May had left the Brussels summit.
The 27 are determined that the UK will pay the relocation bill, as Brexit was a UK decision.
The EMA’s total number of staff in 2015 was 890, while the EBA’s was 189. Both are headquartered in Canary Wharf.
The EMA had 36,000 visitors in 2015, and 30,000 hotel nights were booked, the European Council said.
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